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Dianabol Dbol Cycle Guide, Results, Side Effects And Dosage How medications can cause liver injury (drug‑induced liver injury, DILI)
| Aspect | What happens |
|---|---|
| Mechanism | • Direct hepatotoxicity: the drug or its metabolite damages liver cells (e.g., acetaminophen overdose). • Idiosyncratic reactions: unpredictable immune‑mediated injury after a short latent period (often within weeks to months). |
| Common drugs that trigger DILI | • Acetaminophen (high dose or chronic use) – classic direct toxicity. • Antibiotics (e.g., amoxicillin–clavulanate, fluoroquinolones). • Statins, anti‑epileptics, antiretrovirals, certain anticancer agents. |
| Typical clinical presentation | • Elevated liver enzymes (AST/ALT up to 10× normal). • Possible jaundice or fatigue if injury is severe. • Often asymptomatic |
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